AAV-Induced Cancer: Cause for Concern in Gene Therapy?

By Charlotte Hutchings Gene therapy is an approach to treating or preventing human disorders through the delivery of therapeutic nucleic acids to diseased cells (Lundstrom, 2018). In order to achieve targeted delivery to specific organs and cell types, viruses have been employed as a gene therapy vector as they have naturally evolved to be ableContinue reading “AAV-Induced Cancer: Cause for Concern in Gene Therapy?”

Symptom checkers: how AI could transform the field of diagnostics

By Hannah Scheucher Diagnosis is a patient-specific process to characterize an illness via collection of information, integration of different data and clinical reasoning. In this pursuit, hypotheses of possible conditions explaining a patient’s symptoms are established and eliminated over the course of time. Even with advances in technology and diagnostic testing, diagnostic error still representsContinue reading “Symptom checkers: how AI could transform the field of diagnostics”

Magnetic Blood Filtration as a Promising Treatment for Sepsis

By Cristina Piñel Neparidze Have you ever heard about cytokine storms? Most of the time, when people say that someone has died from COVID-19, the cause of death is simply attributed to the virus and its ability to induce multiple organ failure. We imagine that the unfortunately deceased individual lost their battle against this sneakyContinue reading “Magnetic Blood Filtration as a Promising Treatment for Sepsis”

Target, Transfect, Transect – Using CRISPR to Treat HIV

By Sreenidhi Venkatesh Since their discovery in the 1980s, the human immunodeficiency viruses (HIV) have taken the medical world by storm due to their ability to induce immune system failure, allowing opportunistic infections and cancers to become even more life-threatening.  Currently, the main form of treatment for HIV is anti-retroviral drugs which target various mechanismsContinue reading “Target, Transfect, Transect – Using CRISPR to Treat HIV”

How CRISPR-Cas9 screen cancer targets

By Daniel Lo For the use of CRISPR-Cas, the size and specificity of the sgRNAs make it a highly precise tool for binding to target DNA sequences. The 20 nucleotide sgRNA is an easily modifiable component within the system, and multiple genetic targets can be targeted in the same experiment through the addition of theContinue reading “How CRISPR-Cas9 screen cancer targets”

The Puzzle of Protein Folding

By Ernest Poon In 2003, after 13 years and over $3 billion, the ambitious multinational and multidisciplinary Human Genome Project was completed. Whilst the subsequent conversion of DNA to an amino acid sequence is relatively straightforward, the next step in gene expression – how the amino acid sequence folds to form a polypeptide – isContinue reading “The Puzzle of Protein Folding”

How are seizures detected and prevented in epilepsy?

By Eva Borras According to the World Health Organization, epilepsy is one of the most common neurological diseases on the planet, with roughly 50 million people affected by it, including of age and gender. Epilepsy is a chronic disease characterised for causing recurring seizure episodes of involuntary movements of the body that can lead toContinue reading “How are seizures detected and prevented in epilepsy?”

Cows vs. Climate Change: can genetic engineering resolve the battle?

By Elena Meganck If the world wants to survive the Anthropocene, not only humans but also agriculture will need to adapt to the threat of climate change. Cattle have had a very important role in human evolution, dating back to their domestication some 10,500 years ago in the Fertile Crescent of Mesopotamia. These ruminants have,Continue reading “Cows vs. Climate Change: can genetic engineering resolve the battle?”

Oncogene editing in human papillomavirus (HPV) by CRISPR Cas9

By Daniel Lo Proto-oncogenes are genes that control cell growth. Mutation of a proto-oncogene can be induced by point mutations (insertions and deletions), gene amplification or chromosomal translation. These mutations result in excessive copies of proto-oncogenes, resulting in proto-oncogenes become oncogenes (Chial H, 2008). Oncogenes can be permanently activated leading to uncontrolled cell growth whichContinue reading “Oncogene editing in human papillomavirus (HPV) by CRISPR Cas9”

How jellyfish fight microplastics and Improve soil quality

By Eva Istsenko Humanity is currently producing more amounts of plastic and waste than ever before. There are between 12 and 21 million tons of microplastics floating at the top 200 meters of the Atlantic Ocean (Fact Check: what are microplastics and are they dangerous?, 2020). A small piece of plastic can be considered ‘micro’Continue reading “How jellyfish fight microplastics and Improve soil quality”