Xenobots: Tiny blobs with massive potential

By Heiloi Yip When asked to envision the future of biotechnology, one might think of a couple common images. Some may think about synthetic organisms using tissue pieced together from different species to form a ‘Frankenstein’s monster’. Others may think about a swarm of tiny robots that work together like ants might do, performing aContinueContinue reading “Xenobots: Tiny blobs with massive potential”

Early Drug Discovery Transformation in the Era of Artificial Intelligence

By Anjali Samra Artificial intelligence (AI) related tools are increasingly being used in the early drug discovery pipeline (Reda, Kaufmann & Delahaye-Duriez, 2020). Whilst some are looking towards the vast opportunities that are offered by such tools, there are also many that are opposed, waiting for a clear impact to be seen within the field.ContinueContinue reading “Early Drug Discovery Transformation in the Era of Artificial Intelligence”

The role of viral energy generators in modern biotechnology

By Kilian Robinson Renewable energy generation has never been more important, considering climate change and how much more aware humans are of the impacts of carbon dioxide emissions. Consequently, the search for completely renewable energies has been a prominent topic of discussion in modern day energy generation methods. Despite our recent progress in 2020, inContinueContinue reading “The role of viral energy generators in modern biotechnology”

SUPRA CAR T-Cells: Split, Universal, and Programmable Twist to Cancer Immunotherapy

By Sreenidhi Venkatesh Every year the incidence of cancer continues to increase, taking more than 150,000 lives each year in the UK (Cancer Research UK, n.d.). To combat this complex disease, treatments have evolved to include a plethora of options, including immunotherapy. Cancer immunotherapy involves harnessing the immune system to target and eradicate cancer. ImmunotherapiesContinueContinue reading “SUPRA CAR T-Cells: Split, Universal, and Programmable Twist to Cancer Immunotherapy”

AAV-Induced Cancer: Cause for Concern in Gene Therapy?

By Charlotte Hutchings Gene therapy is an approach to treating or preventing human disorders through the delivery of therapeutic nucleic acids to diseased cells (Lundstrom, 2018). In order to achieve targeted delivery to specific organs and cell types, viruses have been employed as a gene therapy vector as they have naturally evolved to be ableContinueContinue reading “AAV-Induced Cancer: Cause for Concern in Gene Therapy?”

Symptom checkers: how AI could transform the field of diagnostics

By Hannah Scheucher Diagnosis is a patient-specific process to characterize an illness via collection of information, integration of different data and clinical reasoning. In this pursuit, hypotheses of possible conditions explaining a patient’s symptoms are established and eliminated over the course of time. Even with advances in technology and diagnostic testing, diagnostic error still representsContinueContinue reading “Symptom checkers: how AI could transform the field of diagnostics”

Magnetic Blood Filtration as a Promising Treatment for Sepsis

By Cristina Piñel Neparidze Have you ever heard about cytokine storms? Most of the time, when people say that someone has died from COVID-19, the cause of death is simply attributed to the virus and its ability to induce multiple organ failure. We imagine that the unfortunately deceased individual lost their battle against this sneakyContinueContinue reading “Magnetic Blood Filtration as a Promising Treatment for Sepsis”

Target, Transfect, Transect – Using CRISPR to Treat HIV

By Sreenidhi Venkatesh Since their discovery in the 1980s, the human immunodeficiency viruses (HIV) have taken the medical world by storm due to their ability to induce immune system failure, allowing opportunistic infections and cancers to become even more life-threatening.  Currently, the main form of treatment for HIV is anti-retroviral drugs which target various mechanismsContinueContinue reading “Target, Transfect, Transect – Using CRISPR to Treat HIV”

How CRISPR-Cas9 screen cancer targets

By Daniel Lo For the use of CRISPR-Cas, the size and specificity of the sgRNAs make it a highly precise tool for binding to target DNA sequences. The 20 nucleotide sgRNA is an easily modifiable component within the system, and multiple genetic targets can be targeted in the same experiment through the addition of theContinueContinue reading “How CRISPR-Cas9 screen cancer targets”

The Puzzle of Protein Folding

By Ernest Poon In 2003, after 13 years and over $3 billion, the ambitious multinational and multidisciplinary Human Genome Project was completed. Whilst the subsequent conversion of DNA to an amino acid sequence is relatively straightforward, the next step in gene expression – how the amino acid sequence folds to form a polypeptide – isContinueContinue reading “The Puzzle of Protein Folding”