CAR T-cell therapy: A glimpse of hope for cancer patients

By Emmeleia Psyllaki Our bodies are made up of trillions of cells 1. These cells grow and multiply through the process of cell division to form new cells to meet our body’s needs. Sometimes, however, this process becomes disrupted and stops functioning normally. In that case, abnormal or damaged cells multiply and grow when they areContinue reading “CAR T-cell therapy: A glimpse of hope for cancer patients”

Magic mushrooms: a new cure for treatment-resistant depression?

By Sunaina Borkar Over the past few decades, depression has become increasingly prevalent around the world. Although ongoing scientific research has made great strides in the development of effective and accessible mental health treatments, tackling a specific type of depression known as treatment-resistant depression has been a challenge. Treatment-resistant depression currently affects 100 million people,Continue reading “Magic mushrooms: a new cure for treatment-resistant depression?”

Why drinking coffee wakes you up

By Alice de Bernardy Caffeine is considered to be the most widely used drug in the world.1 It is found in many dietary components of our daily lives: not only in coffee and tea, either, but also in soft drinks and even chocolate. While a typical cup of coffee contains around 100 mg of caffeine, its consumption variesContinue reading “Why drinking coffee wakes you up”

What makes G-protein coupled receptors (GPCRs) highly desirable drug targets?

By Nishka Mahajan G-protein coupled receptors (GPCRs) comprise the most extensive class of cell-surface receptors within eukaryotes, with over 820 encoded by the human genome. They are primarily responsible for mediating multiple cell-signalling pathways (physiological processes), making them ideal targets for more than one-third of pharmaceutical applications and therapeutic interventions. Furthermore, their characteristic features ofContinue reading What makes G-protein coupled receptors (GPCRs) highly desirable drug targets?

Managing an evolving relationship between trawling and marine life 

By Alice de Bernardy  Overfishing and ocean pollution are only a portion of the results of today’s fishing activity. Although fishing can be a great and sustainable source of food and income under appropriate scales, the reality remains that a quarter of global fishing comes from trawling activity,  in which immense nets are dragged throughContinue reading “Managing an evolving relationship between trawling and marine life “

A review of erythropoietin and its use in doping

By Anaya Sirothia Upon hearing the term ‘doping’ in sports, many recall the drug scandal involving Lance Armstrong in 2012, or perhaps the disqualification of Festina from 1998’s Tour de France.1 As the news coverage focused primarily on the athletes themselves and the implications of the doping on their respective sports, the science behind theseContinue reading “A review of erythropoietin and its use in doping”

An introduction into NK cell cancer immunotherapy – Pharmaceuticals

By Easha Vigneswaran Cancer, one of the most difficult diseases to treat, is at the forefront of the pharmaceutical world for the development of treatments. From drugs to monoclonal antibodies, all forms of therapy are being tested with many having vast amounts of success. However, inevitably, there are also many cancers that are becoming increasinglyContinue reading An introduction into NK cell cancer immunotherapy – Pharmaceuticals”

Will smoking really reduce your risk of developing Alzheimer’s disease? 

By Themis Halka  Alzheimer’s disease is a preoccupying neurodegenerative disease, and the leading cause of dementia. Treatment of Alzheimer’s disease can only relieve symptoms and slow down neuronal death – there is no cure available to restore the loss of neural tissue. Therefore, acting on the risk factors and finding new neuroprotective agents that couldContinue reading Will smoking really reduce your risk of developing Alzheimer’s disease? 

Bacteriophage therapy: potential solution for antibiotic resistance?

By Nishka Mahajan The technique of bacteriophage or phage therapy, involving the usage of viruses as a remedy for bacterial infections, has existed for about a century now. It was developed based on how phages work: they recognise, bind to, and replicate within bacterial host cells, finally causing cell lysis. However, phage therapy remained aContinue reading Bacteriophage therapy: potential solution for antibiotic resistance?

An introduction to HIV treatments

By Allis Lai Human immunodeficiency virus, or HIV, is one of the leading causes of morbidity and mortality across the globe. The retrovirus attacks the immune system, leading to loss of functional T cells and causing an increased risk of infections, bone disease, kidney and liver dysfunction, and other complications. The virus is transmitted viaContinue reading An introduction to HIV treatments