Antibody-drug conjugates in cancer therapy

By Helen Luojia Zhang Traditional chemotherapy and radiotherapy destroy many types of healthy cells in addition to targeted cancer cells, leading to serious side effects. Antibody-drug conjugates (ADCs) are a class of drug designed as a targeted therapy that specifically deliver the cytotoxic payload to cells that express the target antigen of interest (Khongorzul etContinue reading “Antibody-drug conjugates in cancer therapy”

Autoimmunity: Why does your body attack your own cells?

By MingMing Yang Our immune system is complex and vital for our survival. Unlike other body systems, it is pervasive, spreading throughout our body involving many kinds of cells, organs, and tissues (The immune system: Cells, tissues, function, and disease., 2018). In normal conditions, it recognizes invading pathogens and damaged cells in our body, mountingContinue reading “Autoimmunity: Why does your body attack your own cells?”

The First Step After Paralysis

By Sashini Ranawana It is often easy to take for granted the ability to detect sensory stimuli and bring about voluntary movement. This, however, is not an option for individuals suffering from any one of the numerous forms of paralysis, where the disruption of neuronal signalling between the central nervous system (CNS) and peripheral nervousContinue reading “The First Step After Paralysis”

Symptom checkers: how AI could transform the field of diagnostics

By Hannah Scheucher Diagnosis is a patient-specific process to characterize an illness via collection of information, integration of different data and clinical reasoning. In this pursuit, hypotheses of possible conditions explaining a patient’s symptoms are established and eliminated over the course of time. Even with advances in technology and diagnostic testing, diagnostic error still representsContinue reading “Symptom checkers: how AI could transform the field of diagnostics”

Kindchenschema: The science of cute

By Iulia Kis Even though the English language (and many others) lack a word for the feeling associated with interacting with cute things, there is certainly a specific emotion characteristic to it. This has yet to be pinpointed and thoroughly described, but, ever since ethologist Lorenz Konrad first described what he called the ‘Kindchenschema’ inContinue reading “Kindchenschema: The science of cute”

Magnetic Blood Filtration as a Promising Treatment for Sepsis

By Cristina Piñel Neparidze Have you ever heard about cytokine storms? Most of the time, when people say that someone has died from COVID-19, the cause of death is simply attributed to the virus and its ability to induce multiple organ failure. We imagine that the unfortunately deceased individual lost their battle against this sneakyContinue reading “Magnetic Blood Filtration as a Promising Treatment for Sepsis”

How do plants heal themselves?

By Shi Yeung Plants have a remarkable regeneration capacity that allows them to heal their wounds or even generate new individuals. The regeneration of whole-body plants is exploited widely in plant propagation of certain species by cutting the leaves, cane, or roots, and growing a fully functional plant from this. In this article, we willContinue reading “How do plants heal themselves?”

The Angiogenic Switch

By Mark Comer Sustained angiogenesis is one of the six hallmarks of cancer, presented in the seminal publication by Hanahan & Weingberg in 2000. The ‘switch’ refers to a distinct event during cancer progression where the tumour microenvironment is altered to support growth of new vasculature. The exact steps and pattern of vascularisation are diverseContinue reading “The Angiogenic Switch”

Cancer Stem Cells – Can we combat therapy resistance by targeting their metabolism?

By Hung-Hsi Chen Scientific advancement has allowed for scientists to understand cancer, and to come up with potential therapies that would combat the disease. Cancer stem cells and its metabolism is becoming a popular area of study, with cancer stem cell being one of the major factors contributing to therapy resistance, and cancer metabolism beingContinue reading “Cancer Stem Cells – Can we combat therapy resistance by targeting their metabolism?”

Benefits of exercise in Alzheimer’s disease

By Sarah Choi With lockdown, quarantine, and the pandemic having continued for more than a year, many have been unable to go to the gym, and have had much less opportunity for physical activity. However, while people may be spending an unprecedented amount of time indoors nowadays, the popularisation of exercising at home has providedContinue reading “Benefits of exercise in Alzheimer’s disease”