Improvements in cancer treatment: chemotherapy

By Naveesha Karunanayaka Cancer is a major cause of death around the world with approximately 1 in 6 deaths caused by cancer.1 Cancer is caused by unimpeded cell division and there are various methods to treat it, but these can cause disadvantageous effects to normal cells due to poor selectivity. Chemotherapy, which is a cellContinue reading “Improvements in cancer treatment: chemotherapy”

Updates and new insights into gastroparesis

By Shiyi Liang Gastroparesis (GP) is a chronic situation when patients suffer from slow and abnormal gastric emptying, which means food could not be passed on to the intestine at normal speed. It is characterised by symptoms of early satiety, bloating, abdominal pain, vomiting, and heartburn.1 Based on a study from Minnesota in 2007, theContinue reading “Updates and new insights into gastroparesis”

What is the PICA disorder?

By Anushka Gupta You have probably heard of anorexia nervosa as the most common eating disorder, but do you know what PICA is? According to NEDA (National Eating Disorders Association), it is “eating items that aren’t typically thought of as food and have no significant nutritional value”.1 It is hugely prevalent as it can affectContinue reading What is the PICA disorder?

How sea sponges could be the answer to antibiotic resistance

By Madeleine Eaton In the past century, antimicrobial resistance (AMR) has emerged as a critical global public health threat, threatening our ability to prevent and treat infections ranging from bacterial to fungal. AMR develops in microorganisms due to many reasons including drug efflux pumps, antibiotic inactivation by enzymes, and alterations in metabolic pathways or cellContinue reading How sea sponges could be the answer to antibiotic resistance

Ambrosia and the Promise of Young Blood

By Isabelle Hall In 2016, Ambrosia was founded by Jesse Karmazin. The start-up sought to provide transfusions of blood plasma from people aged 16-25 to patients over 35, at a cost of $8000 per litre. Karmazin claimed that the transfusions had led to positive changes in his clients, appearing to reduce the burden of certainContinue reading “Ambrosia and the Promise of Young Blood”

A Fiery Death: Harnessing Pyroptosis in Disease

By Sarah Choi Cell death and its regulation are integral to human development and function. Indeed, the role of cell death in disease progression further suggests malfunction can have fatal consequences. Over the years, studies on the role of cell death in diseases and the pathways involved has inspired therapeutics that harness the power ofContinue reading “A Fiery Death: Harnessing Pyroptosis in Disease”

Anorexia in different populations

By Shiyi Liang Anorexia is an eating disorder where one loses appetite. Eating disorders affect people’s daily life and can lead to mortality and affects people from all age groups. Various physiological and pathophysiological conditions, as well as psychological problems may lead to anorexia (Yoshimura, Uezono and Ueta, 2015). Anorexia may cause multiple health risks,Continue reading “Anorexia in different populations”

The Dark Reality Behind Cheap Sunglasses

By Elisa Botting Our increasingly interconnected world has led to an explosion in fashion trends and online shopping. These fashion trends have boosted the market for low-priced sunglasses – the small accessory that can cause great damage to your vision when made of poor quality materials. At first glance, ‘affordable’ and easily disposable sunglasses seemContinue reading “The Dark Reality Behind Cheap Sunglasses”

Endometriosis and its link to fertility

By Katherine Bethell  Endometriosis is a condition that affects up to 15% of all women and is the most common cause of chronic pelvic pain (Parasar P et al., 2017). It is a condition characterised by oestrogen-dependent inflammation which affects pelvic tissue, commonly occurring in teenagers and young adults as they begin menstruating (Vercellini PContinue reading “Endometriosis and its link to fertility”

Conducting Clinical Trials for Rare Diseases

By Yuki Agarwala Clinical trials are designed to understand the clinical outcome of particular drugs by observing human subjects in controlled experimental conditions. Clinical trials are conducted with a variety of subjects whose treatments are randomized to limit the inherent confirmation bias of receiving treatment. This allows scientists to determine causality in randomized controlled trialsContinue reading “Conducting Clinical Trials for Rare Diseases”