Flagellar locomotion: assembly, rotation and variation

By Andres Hernandez Maduro With the ever-fluctuating conditions of our world, it is crucial for biological organisms to be able to adapt and respond to external changes in their environment. This is especially true for bacteria, which face a constant struggle to procure limited resources and compete with the many other microscopic species around them.Continue reading Flagellar locomotion: assembly, rotation and variation

Harvesting the microbiota: Faecal Microbiota Transplant

By Kai Yee Eng Our gut is colonized by a group of microorganisms, forming a diverse ecosystem unseen by the naked eye. This colony includes archaea, bacteria, and virus, and they interact with the host in the gut environment, playing a huge role in managing the health of the host.1,2 These tiny organisms bring great impact by involving in key activities suchContinue reading Harvesting the microbiota: Faecal Microbiota Transplant

Magnifying into our body: The vaginal microbiota

By Kai Yee Eng There are a huge number of microorganisms living in and on our bodies. If we look into bacteria only, it is estimated that there are 3.8∙1013 bacteria with a reference man of 70kg, nearly a 1:1 ratio to human cells (~3.0∙1013).1 Although they only accounts for approximately 0.2kg weight1, their significanceContinue reading Magnifying into our body: The vaginal microbiota

Why do we respond differently to the same virus infection?

By Yuchen Lin No one is the same. This is not only true for our appearance and personalities but also for some invisible traits involving genetics. When confronting the same virus infection, such as SARS-CoV-2, different people respond with different symptoms. Lots of people show no or mild symptoms after infection, while others have severeContinue reading Why do we respond differently to the same virus infection?

The gut bacteriome and virome in Covid-19 patients

By Madeleine Pramoedya The bacteriome itself presents a subset of the microbiome which exclusively consists of bacteria. It is the most widely studied and characterised aspect of the gut microbiome.1 It has also long been suggested that the composition of the gut microbiome influences host physiology and plays a strong role in modulating the host’sContinue reading “The gut bacteriome and virome in Covid-19 patients”

Can gut bacteria affect your mental health?

By Asra Shah Most people have experienced situations where they have “gone with their gut”, but have you ever wondered what that means? In such situations, unexpected signals are received from a “second brain” hidden deep in the walls of the digestive system—the Enteric Nervous System (ENS), a main division of the Autonomic Nervous SystemContinue reading Can gut bacteria affect your mental health?

The role of the gut microbiota in Alzheimer’s disease

By Michelle Lam Alzheimer’s disease (AD) is the leading cause of dementia, affecting over 50 million people worldwide.1 With improvements in global health, dementia cases are projected to triple by 2050.2 Despite advancements in understanding disease progression, there are still no disease-modifying therapies available. Therefore, it is crucial that new biomarkers are identified to overcomeContinue reading The role of the gut microbiota in Alzheimer’s disease

The gut microbiome and colorectal cancer

By Kai Yee Eng The human microbiome consists of a diverse set of microorganisms, from bacteria, to viruses, archaea, and other eukaryotic microbes. These microorganisms play a huge role in maintaining immune health – to the extent that they are regarded as “the hidden organ” (Guinane and Cotter, 2013). The largest portion of the humanContinue reading The gut microbiome and colorectal cancer

Antimicrobial Resistance and COVID-19

By Linya Thng The highly infectious coronavirus illness 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is a health concern throughout the world. COVID-19 emerged as a global pandemic responsible for over 2.9 million deaths – the highest mortality rate since the era of the 1918 Influenza pandemic (Hassan etContinue reading “Antimicrobial Resistance and COVID-19”

The battle of the ages: Cancer vs Virus

By Jessie Ng Chi Wai An oncolytic virus is a type of replicable virus which infects and kills cancer cells. Oncolytic virus therapy is now highly regarded among cancer treatments, as it has shown excellent capability in stimulating an immune response against cancer without causing harm to other healthy tissues.          Reports of viral infectionsContinue reading “The battle of the ages: Cancer vs Virus”