Could spider venom be the cure for Irritable Bowel Syndrome?

By Yeji Hong Chronic pain is a frequent condition that affects approximately 20% of the world population. It is recognised as pain that persists longer than normal healing time, recurring for more than 3~6 months (Treede et al., 2015). Chronic visceral pain forms a major component of several gastrointestinal and bladder disorders including irritable bowelContinue reading “Could spider venom be the cure for Irritable Bowel Syndrome?”

Hormone Sensitive Lipase, a therapeutic target for type 2 diabetes mellitus?

By Cristina Riquelme Vano In 2000, 171 million people were suffering with diabetes. Due to an increase in people being diagnosed with obesity and sedentarism, this number is expected to double by 2030 (Wild et al., 2004). Type 2 diabetes, the most common type, is a chronic condition that affects the way the human bodyContinue reading “Hormone Sensitive Lipase, a therapeutic target for type 2 diabetes mellitus?”

Unlocking a Super Power: Regeneration

By Thanya (Safi) Siamwalla The fascinating ability of some animals to regenerate body parts has captured the imagination of scientists for decades (Echeverri,1969). Incredible regenerative talents are widespread in the animal kingdom. Invertebrates are capable of re-growing almost their entire body. A common example of this is the Planarian flatworm, which deploys adult pluripotent stem cellsContinue reading “Unlocking a Super Power: Regeneration”

Application of monoclonal antibodies to treat COVID-19

By Adriana Ramos Calvo COVID-19, the disease caused by the novel virus SARS-CoV-2, is expanding rapidly, causing countries that had previously relaxed their precautionary measures to go back into lockdown and marking the development of treatment strategies as one of researchers’ top priorities. During these last months, a great deal of effort has been putContinue reading “Application of monoclonal antibodies to treat COVID-19”

Alternative splicing: the future of cancer treatment?

By Samantha Yates Alternative splicing is a form of messenger RNA (mRNA) splicing by which many different protein isoforms are produced. Alternative splicing rearranges and combines exons in different positions to alter the mRNA coding sequence and is the main source of protein diversity in >90% of human genes. Due to its tightly regulated processContinue reading “Alternative splicing: the future of cancer treatment?”

Aboriginal Bush Medicine – Uses of Kangaroo Apple

By Isabelle Hall Traditional healing methods have been practised by Aboriginal groups in Australia for over 60 000 years. Among indigenous communities, the use of specific medical treatments varies according to location and cultural convention. In the state of Victoria, Gukwonderuk (Centipeda cunninghamii, also known as Old Man’s Weed) has been used by the WotjobalukContinue reading “Aboriginal Bush Medicine – Uses of Kangaroo Apple”

The role of amino acids in cancer metabolism

By Hung-Hsi (Chelsea) Chen Serine is a non-essential amino acid derived from glycine. In healthy individuals, serine is important for the proper function of the brain, especially the central nervous system (CNS), production of nucleotides, muscle formation, immune system and fatty acid metabolism. However, a vital amino acid such as serine can also contribute toContinue reading “The role of amino acids in cancer metabolism”

Antifungal resistance: an overlooked killer

By Samrah Siddiqi  The advancement of modern medicine has emerged with many challenges. The misuse and overuse of antibiotics is a familiar concept to all. Antimicrobial resistance (AMR) is a term which has been in the limelight for the past several decades, with growing focus on antibacterial resistance. However, problems associated with antifungal resistance, which is equally as deadly, have often been overlooked (Helen Albert, 20202). In 2018, the UK government put aside £20 million outContinue reading “Antifungal resistance: an overlooked killer”

What are mRNA Vaccines and Are They the Future of Vaccinations?

By Marina Artemiou Vaccines are biological substances that provide a simple, safe and effective way of protecting humans against harmful pathogens and the disorders that are caused upon infection. Vaccinations are considered to be one of the major achievements of modern medicine; since their discovery, the incidence of highly contagious and deadly diseases, such asContinue reading “What are mRNA Vaccines and Are They the Future of Vaccinations?”

Cancer Immunotherapy: Immune Checkpoint Blockade

By Clarice Tse The immune system is the human body’s greatest defense, therefore, scientists eagerly research new ways of manipulating immune mechanisms to combat diseases, for example cancer.  As scientists have learned more about the immune system, they have been able to integrate their knowledge with cancer biology to develop immunotherapy. The importance of immunotherapyContinue reading “Cancer Immunotherapy: Immune Checkpoint Blockade”